The purpose of this document is to provide an overview of the handover of the HIV program to the Bureau of Health (BoH) in the Kahsay Abera Hospital (KAH), Humera, Ethiopia, in 2007. The lessons learnt during the handover process could be of value to other MSF teams faced with an impeding handover of activities to the local health structure. A document in this vein was written directly following the handover in July 2007 however this current text acts as an updated version using the knowledge gained during the ten months following handover. It seems that during this ten months additional points have come to light or been identified that will assist in formulating a more thorough and accurate ‘lesson learnt’ document.